Subgingival chlorhexidine irrigation for scaling and root planing adjunctive therapy in chronic periodontitis: a systematic review

BACKGROUND Scaling and root planing (SRP) is a conventional treatment for chronic periodontitis; however, it has limitations in treating deep pockets. To enhance its efficacy, chlorhexidine (CHX) proposed as adjunctive therapy with SRP due to broad antimicrobial spectrum, low systemic toxic activity humans, absence of oral microorganism resistance, lack teratogenic effects. This study aimed know the efficacy CHX.
 METHODS A literature search was conducted using various databases including PubMed, LIVIVO, EBSCOhost, Google Scholar, following Preferred Reporting Items Systematic Review Meta-Analyses guidelines within last 10 years (2011–2021). Clinical parameters such plaque index (PI), gingival (GI), bleeding on probing (BOP), pocket depth (PD), clinical attachment level (CAL) were recorded. The risk bias selected studies assessed Cochrane Collaboration’s Handbook version 5.2.0.
 RESULTS Of 368 studies, met inclusion criteria, 8 them having higher quality. Higher reduction PI, GI, BI, PD, CAL observed CHX irrigation compared alone.
 CONCLUSIONS Overall, adding appeared have additional benefits alone periodontitis.